Pharmacognosy Lab

2022

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113. Chaeyeong Kim, Soo Ho Ryu, Hyukjae Choi, Dong Ho Park, and Jong-Sup Bae* "The Inhibitory Functions of Sparstolonin B against Ambient Fine Particulate Matter Induced Lung Injury" Biotechnology and Bioprocess Engineering, 2022, 27, 949-960. DOI: 10.1007/s12257-022-0286-3.

 

112. Gwi Ja Hwang, Mina Jang, Sangkeun Son, Gil Soo Kim, Byeongsan Lee, Kyung Taek Heo, Geum Jin Kim, Hyukjae Choi, Jae-Seoun Hur, Jun-Pil Jang, Sung-Kyun Ko, Young-Soo Hong,* Jong Seog Ahn,* and Jae-Hyuk Jang* "Ulleungdolin, a Polyketide−Peptide Hybrid Bearing a 2,4- Di‑O‑methyl-β‑D‑antiarose from Streptomyces sp. 13F051 Cocultured with Leohumicola minima 15S071" Journal of Natural Products, 2022, 85, 2445-2453. DOI: 10.1021/acs.jnatprod.2c00682.

 

111. Yun-Seo Kil, Ananda Baral, Byeong-Seon Jeong, Pekka Laatikainen, Yang Liu, Ah-Reum Han, Min-Jeong Hong, Jin-Baek Kim, Hyukjae Choi, Pil-Hoon Park,* and Joo-Won Nam* "Combining NMR and MS to Describe Pyrrole-2-Carbaldehydes in Wheat Bran of Radiation" Journal of Agricultural and Food Chemistry, 2022, 70, 13002-13014. DOI: 10.1021/acs.jafc.2c04771.

 

110. Trung Huy Ngo, Ajay Uprety, Manju Ojha, Yun-Seo Kil, Hyukjae Choi, Soo Young Kim,* and Joo-Won Nam* "Stability of valeriana-type iridoid glycosides from rhizomes of Nardostachys jatamansi and their protection against H2O2-induced oxidative stress in SH-SY5Y cells" Phytochemistry, 2022, 203, 113375. DOI: 10.1016/j.phytochem.2022.113375.

 

109. Dongyup Hahn, Weihong Wang, Hyukjae Choi* and Heonjoong Kang* "Determination of sequence and absolute confguration of peptide amino acids by HPLC–MS/CD‑based detection of liberated N‑terminus phenylthiohydantoin amino acids" Scientific Reports, 2022, 12, 10285. DOI: 10.1038/s41598-022-14205-x.

 

108. Sina Shadfar,* Shristi Khanal, Ganesh Bohara, Geum Jin Kim, Saeed Sadigh‑Eteghad, Saeid Ghavami, Hyukjae Choi, and Dong‑Young Choi "Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone‑Induced Neurotoxicity" Molecular Neurobiology, 2022, 59, 5874-5890. DOI: 10.1007/s12035-022-02943-y.

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107. Sunil Babu Paudel, Tiep Tien Nguyen, Yun-Seo Kil, Hyukjae Choi, Jee-Heon Jeong,* and Joo-WonNam* "Tricyclic diterpenes from the resin of Daemonorops draco and their activities on oxidative stress-induced mesenchymal stromal cells" Phytochemistry Letters, 2022, 50, 106-111. DOI: 10.1016/j.phytol.2022.05.012.

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106. Ming Gao, Sang Bong Lee, Jae-Eon Lee, Geum Jin Kim, Jimin Moon, Joo-Won Nam, Jong-Sup Bae, Jungwook Chin, Yong Hyun Jeon*, and Hyukjae Choi* "Anti-Inflammatory Butenolides from a Marine-Derived Streptomyces sp. 13G036" Applied Sciences, 2022, 12, 4510.  DOI: 10.3390/app12094510.

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105. Punam Thapa, Hye Mi Kim, Joon-Pyo Hong, Ranhee Kim, Sunil Babu Paudel, Hyukjae Choi, Dae Sik Jang*, and Joo-Won Nam* "Absolute Quantification of Isoflavones in the Flowers of Pueraria lobata by qHNMR" Plants (Basel), 2022, 11, 548.  DOI: 10.3390/plants11040548.

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104. Tu Cam Le, Sultan Pulat, Jihye Lee, Geum Jin Kim, Haerin Kim, Eun-Young Lee, Prima F Hillman, Hyukjae Choi, Inho Yang, Dong-Chan Oh, Hangun Kim, Sang-Jip Nam*, and William Fenical* "Marine Depsipeptide Nobilamide I Inhibits Cancer Cell Motility and Tumorigenicity via Suppressing Epithelial-Mesenchymal Transition and MMP2/9 Expression" ACS Omega, 2022, 7, 1722-1732.  DOI: 10.1021/acsomega.1c04520.

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103. Yun-Seo Kil, Ah-Reum Han, Min-Jeong Hong, Jin-Baek Kim, Pil-Hoon Park, Hyukjae Choi, and Joo-Won Nam* "1H NMR-Based Chemometrics to Gain Insights Into the Bran of Radiation-Induced Colored Wheat Mutant" Frontiers in Nutrition, 2022, 8, 806744.  DOI: 10.3389/fnut.2021.806744.

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102. Geum Jin Kim, Samantha J Mascuch, Emily Mevers, Paul D Boudreau, William H Gerwick*, and Hyukjae Choi* "Luquilloamides, Cytotoxic Lipopeptides from a Puerto Rican Collection of the Filamentous Marine Cyanobacterium Oscillatoria sp." The Journal of Organic Chemistry, 2022, 87, 1043-1055.  DOI: 10.1021/acs.joc.1c02340.

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2021

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101. Ah-Reum Han, Hae Ran Park, Geum Jin Kim, Bo-Ram Kim, Ye-Ram Kim, Hyeon Hwa Park, Jisu Park, Chang Hyun Jin, Jung Min Kim, Soon-Jae Kwon, Jin-Baek Kim, Shugeng Cao, Joo-Won Nam, Hyukjae Choi* "18:0 Lyso PC Derived by Bioactivity-Based Molecular Networking from Lentil Mutant Lines and Its Effects on High-Fat Diet-Induced Obese Mice" Molecules, 2021, 26, 7547. DOI: 10.3390/molecules26247547.

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100. Mi-Rae Shin, Jin A Lee, Minju Kim, Sehui Lee, Minhyuck Oh, Jimin Moon, Joo-Won Nam, Hyukjae Choi, Yeun-Ja Mun, and Seong-Soo Roh* "Gardeniae Fructus Attenuates Thioacetamide-Induced Liver Fibrosis in Mice via Both AMPK/SIRT1/NF-κB Pathway and Nrf2 Signaling" Antioxidants (Basel). 2021, 10, 1837. DOI: 10.3390/antiox10111837.

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99. Hiyoung Kim, Tae Gu Lee, Inho Yang, Weihong Wang, Jungwook Chin, Jusung Lee, Boon Jo Rho, Hyukjae Choi, Sang-Jip Nam, Dongyup Hahn*, and Heonjoong Kang* "Antibacterial Bicyclic Fatty Acids from a Korean Colonial Tunicate Didemnum sp." Marine Drugs, 2021, 19, 521. DOI: 10.3390/md19090521.

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98. Bo-Ram Kim, Sunil Babu Paudel, Ah-Reum Han, Jisu Park, Yun-Seo Kil, Hyukjae Choi, Yeo Gyeong Jeon, Kong Young Park, Si-Yong Kang, Chang Hyun Jin, Jin-Baek Kim, and Joo-Won Nam* "Metabolite profiling and dipeptidyl peptidase IV inhibitory activity of Coreopsis cultivars in different mutations" Plants (Basel), 2021, 10, 1661. DOI: 10.3390/plants10081661.

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97. So Young Kim, Myoung-Sook Shin, Geum Jin Kim, Hyukbean Kwon, Myong Jin Lee, Ah-Reum Han, Joo-Won Nam, Chan-Hun Jung, Ki Sung Kang*, and Hyukjae Choi* "Inhibition of A549 lung cancer cell migration and invasion by ent-caprolactin C via the suppression of transforming growth factor-β-induced epithelial-mesenchymal transition" Marine Drugs, 2021, 19, 465. DOI: 10.3390/md19080465.

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96. Sojeong Kim, Chang Wook Lee, So-Yeon Park, Ratnakar N Asolkar, Haerin Kim, Geum Jin Kim, Song Jin Oh, Youngbae Kim, Eun-Young Lee, Dong-Chan Oh, Inho Yang, Man Jeong Paik, Hyukjae Choi, Hangun Kim*, Sang-Jip Nam*, and William Fenical* "Acremonamide, a cyclic pentadepsipeptide with wound-healing properties isolated from a marine-derived fungus of the genus Acremonium" Journal of Natural Products, 2021, 84, 2249-2255. DOI: 10.1021/acs.jnatprod.1c00305.

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95. Sunghee Bang, Ji Yun Baek, Geum Jin Kim, Jaekyeong Kim, SungJin Kim, Stephen T Deyrup, Hyukjae Choi, Ki Sung Kang*, and Sang Hee Shim* "Azaphilones from an endophytic Penicillium sp. prevent neuronal cell death via inhibition of MAPKs and reduction of Bax/Bcl-2 ratio" Journal of Natural Products, 2021, 84, 2226-2237. DOI: 10.1021/acs.jnatprod.1c00298.

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94. Zhexue Wu, Geum Jin Kim, So-Young Park, Jong Cheol Shon, Kwang-Hyeon Liu*, and Hyukjae Choi* "In vitro metabolism study of seongsanamide A in human liver microsomes using non-targeted metabolomics and feature-based molecular networking" Pharmaceutics, 2021, 13, 1031. DOI: 10.3390/pharmaceutics13071031.

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93. Ji Hwan Lee, Sullim Lee, Quynh Nhu Nguyen, Hung Manh Phung, Myoung-Sook Shin, Jae-Yong Kim, Hyukjae Choi, Sang Hee Shim*, and Ki Sung Kang* "Identification of the active ingredient and beneficial effects of Vitex rotundifolia fruits on menopausal symptoms in ovariectomized rats" Biomolecules, 2021, 11, 1033. DOI: 10.3390/biom11071033.

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92. Hae-Jung Chae, Geum Jin Kim, Barsha Deshar, Hyun-Jin Kim, Min-Ji Shin, Hyukbean Kwon, Ui-Joung Youn, Joo-Won Nam, Sung-Hak Kim, Hyukjae Choi*, and Sung-Suk Suh* "Anticancer activity of 2-O-caffeoyl alphitolic acid extracted from the lichen, Usnea barbata 2017-KL-10" Molecules, 2021, 26, 3937. DOI: 10.3390/molecules26133937.

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91. Tara Man Kadayat, Dong Eun Kim, Sang Bong Lee, Kyungjin Jung, Sang Eun Park, Ji-Ye Hong, Jina Kim, Aarajana Shrestha, Dong-Su Kim, Hongchan An, Nayeon Kim, Su-Jeong Lee, Sugyeong Kwon, Suhui Kim, Jun Yeon Hwang, Shinae Kim, Dongyup Hahn, Hyukjae Choi, Sang-Jip Nam, Yong Hyun Jeon, Jung Jin Hwang, Sung Jin Cho*, and Jungwook Chin* "Antioxidative and anti-inflammatory activity of psiguadial B and its halogenated analogues as potential neuroprotective agents" Bioorganic Chemistry, 2021, 113, 105027. DOI: 10.1016/j.bioorg.2021.105027.

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90. Sullim Lee, Geum Jin Kim, Hyukbean Kwon, Joo-Won Nam, Ji Yun Baek, Sang Hee Shim, Hyukjae Choi*, and Ki Sung Kang* "Estrogenic effects of extracts and isolated compounds from belowground and aerial parts of Spartina anglica" Marine Drugs, 2021, 19, 210. DOI: 10.3390/md19040210.

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89. Punam Thapa, Yoo Jin Lee, Tiep Tien Nguyen, Donglan Piao, Hwaryeong Lee, Sujin Han, Yeon Jin Lee, Ah-Reum Han, Hyukjae Choi, Jee-Heon Jeong, Joo-Won Nam*, and Eun Kyoung Seo* "Eudesmane and eremophilane sesquiterpenes from the fruits of Alpinia oxyphylla with protective effects against oxidative stress in adipose-derived mesenchymal stem cells" Molecules, 2021, 26, 1762. DOI: 10.3390/molecules26061762.

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88. Manju Ojha, Yun-Seo Kil, Ui Joung Youn, Young Jun Ok, Hyukjae Choi, and Joo-Won Nam* "Compositional variation of atranorin-related components of lichen Myelochroa leucotyliza dependent on extraction solvent and their quantitative analysis by qHNMR" Phytochemical Analysis, 2021, Ahead of print. DOI: 10.1002/pca.3048.

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87. Geum Jin Kim, Songhee Park, Eonmi Kim, Hyukbean Kwon, Hae-Jin Park, Joo-Won Nam, Seong-Soo Roh*, and Hyukjae Choi* "Antioxidant, pancreatic lipase inhibitory, and tyrosinase inhibitory activities of extracts of the invasive plant Spartina anglica (Cord-grass) " Antioxidants, 2021, 10, 242. DOI: 10.3390/antiox10020242.

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86. Punam Thapa, Nikita Katila, Dong-Young Choi*, Hyukjae Choi*, and Joo-Won Nam* "Suntamide A, a neuroprotective cyclic peptide from Cicadidae Periostracum" Bioorganic Chemistry, 2021, 106, 104493. DOI: 10.1016/j.bioorg.2020.104493.

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85. Eonmi Kim, Sae-Kwang Ku, Sumin Yang, Bong-Seon Lee, Geum Jin Kim, Hyukjae Choi,* and Jong-Sup Bae* "Collismycin C reduces HMGB1-mediated septic responses and improves survival rate in septic mice" Journal of Asian Natural Products Research, 2021, 23, 55-72. https://doi.org/10.1080/10286020.2019.1706497

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2020

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84. Ji Won Choi, Geum Jin Kim, Hyeon Jeong Kim, Joo-Won Nam, Jushin Kim, Jungwook Chin, Jong-Hyun Park, Hyukjae Choi*, and Ki Duk Park* "Identification and evaluation of a napyradiomycin as a potent Nrf2 activator: Anti-oxidative and anti-inflammatory activitie" Bioorganic Chemistry, 2020, 105, 104434. DOI: 10.1016/j.bioorg.2020.104434.

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83. Sunil Babu Paudel, Ah-Reum Han, Hyukjae Choi, and Joo-Won Nam* "Phytochemical constituents of leaves and twigs of Elaeagnus umbellata" Biochemical Systematics and Ecology, 2020, 93, 104178. DOI: 10.1016/j.bse.2020.104178.

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82. Jihye Lee, Chathurika D B Gamage, Geum Jin Kim, Prima F Hillman, Chaeyoung Lee, Eun Young Lee, Hyukjae Choi, Hangun Kim,* Sang-Jip Nam,* and William Fenical* "Androsamide, a Cyclic Tetrapeptide from a Marine Nocardiopsis sp., Suppresses Motility of Colorectal Cancer Cells" Journal of Natural Products, 2020, 83, 3166-3172. DOI: 10.1021/acs.jnatprod.0c00815

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81. Punam Thapa, Ye Gu, Yun-Seo Kil, Su Cheol Baek, Ki Hyun Kim, Ah-Reum Han, Eun Kyoung Seo, Hyukjae Choi, Jae-Hoon Chang,* and Joo-Won Nam* "N-Acetyldopamine derivatives from Periostracum Cicadae and their regulatory activities on Th1 and Th17 cell differentiation" Bioorganic Chemistry, 2020, 102, 104095. DOI: 10.1016/j.bioorg.2020.104095.

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80. Mahesh Sapkota, Ming Gao, Liang Li, Ming Yang, Saroj Kumar Shrestha, Hyukjae Choi,* and Yunjo Soh* "Macrolactin A protects against LPS-induced bone loss by regulation of bone remodeling" European Journal of Pharmacology, 2020, 883, 173305. DOI: 10.1016/j.ejphar.2020.173305.

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79. Gil Soo Kim, Geum Jin Kim, Byeongsan Lee, Tae Hoon Oh, Mincheol Kwon, Jung-Sook Lee, Jun-Pil Jang, Hyukjae Choi, Sung-Kyun Ko, Young-Soo Hong, Jae-Hyuk Jang,* and Jong Seog Ahn* "Highly oxygenated angucycline from Streptomyces sp. KCB15JA014" The Journal of Antibiotics, 2020, Online ahead of print. DOI: 10.1038/s41429-020-0348-8.

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78. Pisey Pel, Hee-Sung Chae, Piseth Nhoek, Young-Mi Kim, Piseth Khiev, Geum Jin Kim, Joo-Won Nam, Hyukjae Choi, Young Hee Choi, and Young-Won Chin* "A stilbene dimer and flavonoids from the aerial parts of Chromolaena odorata with proprotein convertase subtilisin/kexin type 9 expression inhibitory activity" Bioorganic Chemistry, 2020, 99, 103869. DOI: 10.1016/j.bioorg.2020.103869.

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77. Bushra Shal, Adnan Khan, Muhammad Naveed, Hussain Ali, Eun Kyoung Seo, Hyukjae Choi, and Salman Khan* "Neuroprotective effect of 25-methoxyhispidol A against CCl 4-induced behavioral alterations by targeting VEGF/BDNF and caspase-3 in mice" Life Sciences, 2020, 253, 117684. DOI: 10.1016/j.lfs.2020.117684.

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76. Tu Cam Le, Nikita Katila, Songhee Park, Jihye Lee, Inho Yang, Hyukjae Choi,* Dong-Young Choi,* and Sang-Jip Nam* "Two new secondary metabolites, saccharochlorines A and B, from a marine bacterium Saccharomonospora sp. KCTC-19160" Bioorganic & Medicinal Chemistry Letters, 2020, 30, 127145. DOI: 10.1016/j.bmcl.2020.127145.

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75. Bo-Ram Kim, Punam Thapa, Hyun Mi Kim, Chang Hyun Jin, Sang Hoon Kim, Jin-Baek Kim, Hyukjae Choi, Ah-Reum Han,* and Joo-Won Nam* "Purification of phenylpropanoids from the scaly bulbs of Lilium longiflorum by CPC and determination of their DPP-IV inhibitory potentials" ACS Omega, 2020, 5, 4050-4057. DOI: 10.1021/acsomega.9b03649.

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74. Sailesh Maharjan, Sang Bong Lee, Geum Jin Kim, Sung Jin Cho, Joo-Won Nam, Jungwook Chin,* and Hyukjae Choi* "Isolation of unstable isomers of lucilactaene and evaluation of anti-inflammatory activity of secondary metabolites produced by the endophytic fungus Fusarium sp. QF001 from the roots of Scutellaria baicalensis " Molecules, 2020, 25, 923.

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73. Bong-Seon Lee, Eonmi Kim, Hyukjae Choi,* and Jong-Sup Bae* "Suppressive functions of collismycin C in TGFBIp-mediated septic responses" Journal of Natural Medicines, 2020, 74, 387-398.

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72. Eun-Nam Kim, Ming Gao, Hyukjae Choi,* and Gil-Saeng Jeong* "Marine microorganism-derived macrolactins inhibit inflammatory mediator effects in LPS-induced macrophage and microglial cells by regulating BACH1 and HO-1/Nrf2 signals through inhibition of TLR4 activation." Molecules, 2020, 25, 656.

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71. Eonmi Kim, Sae-Kwang Ku, Sumin Yang, Bong-Seon Lee, Geum Jin Kim, Hyukjae Choi,* and Jong-Sup Bae* "Collismycin C reduces HMGB1-mediated septic responses and improves survival rate in septic mice" Journal of Asian Natural Products Research, 2019, Epub ahead of print. https://doi.org/10.1080/10286020.2019.1706497

 

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2019

 

70. Hyun Gyu Choi, Jung Wha Kim, Hyukjae Choi, Ki Sung Kang, and Sang Hee Shim* "New hydroxydecanoic acid derivatives produced by an endophytic yeast Aureobasidium pullulans AJF1 from flowers of Aconitum carmichaeli" Molecules, 2019, 24, 4051.

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69. Sunil Babu Paudel, Jiyoung Park, Nam Hee Kim, Hyukjae Choi, Eun-Kyoung Seo, Hyun Ae Woo,* and Joo-Won Nam* "Constituents of the leaves and twigs of Elaeagnus umbellata and their proliferative effects on human keratinocyte HaCaT cells" Fitoterapia, 2019, 139, 104374.

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68. Jaewoo Yoon, Sailesh Maharjan, and Hyukjae Choi* "Polyphasic taxonomic analysis of Paracoccus ravus sp. nov., an alphaproteobacterium isolated from marine sediment" FEMS Microbiology Letters, 2019, 366, 184.

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67. Hyukjae Choi, Wonhwa Lee, Eonmi Kim, Sae-Kwang Ku* and Jong-Sup Bae* "Inhibitory effects of collismycin C and pyrisulfoxin A on particulate matter-induced pulmonary injury" Phytomedicine, 2019, 62, 152939.

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66. Sae-Kwang Ku, So Yeon Jeong, Sumin Yang, Kyung-Min Kim, Hyukjae Choi,* and Jong-Sup Bae* "Suppressive effect of collismycin C on polyphosphate-mediated vascular inflammatory response" Fitoterapia, 2019, 134, 447-453.

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65. Jihye Lee, Jusung Lee, Geum Jin Kim, Inho Yang, Weihong Wang, Joo-Won Nam, Hyukjae Choi, Sang-Jip Nam* and Heonjoong Kang* "Mycousfurans A and B, antibacterial usnic acid congeners from the fungus Mycosphaerella sp., isolated from a marine sediment" Marine Drugs, 2019, 17, 422.

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64. Yifeng Deng, Fansi Jin, Xian Li, Sung Joon Park, Jae-Hoon Chang, Dong-Young Kim, Jung-Ae Kim, Joo-Won Nam, Hyukjae Choi, Youn Ju Lee*, and Hyeun Wook Chang* "Sauchinone suppresses FcεRI-mediated mast cell signaling and anaphylaxis through regulation of LKB1/AMPK axis and SHP-1-Syk signaling module" International Immunopharmacology, 2019, 74, 105702.

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63. Sunil Srivastav, Sabita Neupane, Sunil Bhurtel, Nikita Katila, Sailesh Maharjan, Hyukjae Choi, Jin Tae Hong, Dong-Young Choi* "Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity" Journal of Nutritional Biochemistry, 2019, 69, 73-86.

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62. Tu Cam Le, Eun Ju Lee, Jihye Lee, Ahreum Hong, Chae-Yoon Yim, Inho Yang, Hyukjae Choi, Jungwook Chin, Sung Jin Cho, Jaeyoung Ko, Hayoung Hwang, Sang-Jip Nam*, and William Fenical* "Saccharoquinoline, a cytotoxic alkaloidal meroterpenoid from marine-derived bacterium Saccharomonospora sp." Marine Drugs, 2019, 17, 98.

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61. Hyukjae Choi,* Niclas Engene, Tara Byrum, Sunghoon Hwang, Dong-Chan Oh and William H. Gerwick* "Dragocins A-D, structurally intriguing cytotoxic metabolites from a Panamanian marine cyanobacterium" Organic Letters, 2019, 21, 266-270.

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2018

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60. Geum Jin Kim, Xian Li, Seong-Hwan Kim, Inho Yang, Dongyup Hahn, Jungwook Chin, Sang-Jip Nam, Joo-Won Nam, Doo Hyun Nam, Dong-Chan Oh, Hyeun Wook Chang* and Hyukjae Choi* "Seongsanamides A–D: anti-allergic bicyclic peptides from Bacillus safensis KCTC 12796BP" Organic Letters, 2018, 20, 7539-7543.

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59. Nguyen Phan Kieu Hanh, Soo Hee Kim, Geum Jin Kim, Hyukjae Choi* and Doo Hyun Nam* "The complete genome sequence of a marine sponge-associated bacteria, Bacillus safensis KCTC 12796BP, which produces a series of anti-allergic compounds" Korean Journal of Microbiology, 2018, 54, 448-452.

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58. Inho Yang, Jusung Lee, Jihye Lee, Dongyup Hahn, Jungwook Chin, Dong Hwan Won, Jaeyoung Ko, Hyukjae Choi, Ahreum Hong, Sang-Jip Nam* and Heonjoong Kang* "Scalalactams A-D, scalarane sesterterpenes with a γ-lactam moiety from a Korean marine sponge Spongia sp." Molecules, 2018, 23, 3187.

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57. Nguyen Phan Kieu Hanh, Jae Yoon Hwang, Hye Ryeung Oh, Geum Jin Kim, Hyukjae Choi and Doo Hyun Nam* "Biosynthesis of 2-amino-3-hydroxycyclopent-2-enone moiety of bafilomycin in Kitasatospora cheerisanensis KCTC2395" Journal of Microbiology, 2018, 56, 571-578.

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56. Jong Y. Lee, Geum J. Kim, Jin K. Choi1, Young-Ae Choi, Na-Hee Jeong, Pil-Hoon Park, Hyukjae Choi* and Sang-Hyun Kim* "4-(Hydroxymethyl)catechol extracted from fungi in marine sponges attenuates rheumatoid arthritis by inhibiting PI3K/Akt/NF-κB signaling" Frontiers in Pharmacology, 2018, 9, 726.

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55. Dayoung Kim, Eun Ju Lee, Jihye Lee, Alain S. Leutou, Yern-Hyerk Shin, Bomi Choi, Ji Sun Hwang, Dongyup Hahn, Hyukjae Choi, Jungwook Chin, Sung Jin Cho, Yong Deog Hong, Jaeyoung Ko, Chi Nam Seong, Katherine N. Maloney, Dong-Chan Oh, Inho Yang*, Hayoung Hwang* and Sang-Jip Nam* "Antartin, a cytotoxic Zizaanet-type sesquiterpenoid from a Streptomyces sp. isolated from an antarctic marine sediment" Marine Drugs, 2018, 16, 130.

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54. Kyo Bin Kang, Ming Gao, Geum Jin Kim, Hyukjae Choi* and Sang Hyun Sung* "Rhamnellosides A and B, ω-phenylpentaene fatty acid amide diglycosides from the fruits of Rhamnella franguloides" Molecules, 2018, 23, 752.

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53 Samantha J. Mascuch, Paul D. Boudreau, Tristan M. Carland, N. Tessa Pierce, Joshua Olson, Mary E. Hensler, Hyukjae Choi, Joseph Campanale, Amro Hamdoun, Victor Nizet, William H. Gerwick, Teresa Gaasterland* and Lena Gerwick* "Marine natural product honaucin A attenuates inflammation by activating the Nrf2-ARE pathway" Journal of Natural Products, 2018, 81(3), 506-514.

 

 

2017

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52. Jin Kyeong Choi, Yong Hyun Jang, Soyoung Lee, Sang-Rae Lee, Young-Ae Choi, Meiling Jin, Jung Ho Choi, Jee Hun Park, Pil-Hoon Park, Hyukjae Choi, Taeg Kyu Kwon, Dongwoo Khang∗ and Sang-Hyun Kim* "Chrysin attenuates atopic dermatitis by suppressing inflammation of keratinocytes" Food and Chemical Toxicology, 2017, 110, 142-150.

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51. Tae In Kim, Bora Shin, Geum Jin Kim, Hyukjae Choi, Chong Soon Lee, Mi Hee Woo, Dong-Chan Oh and Jong Keun Son* "DNA topoisomerase inhibitory activity of constituents from the fruits of Illicium verum" Chemical and Pharmaceutical Bulletin, 2017, 65, 1179-1184.

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50. Jin-Hyung Lee, Eonmi Kim, Hyukjae Choi* and Jintae Lee* "Collismycin C from the micronesian marine bacterium Streptomyces sp. MC025 inhibits Staphylococcus aureus biofilm formation" Marine Drugs, 2017, 15, 387.

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49. Yeon-Yong Kim, Soyoung Lee, Min-Jong Kim, Byeong-Cheol Kang, Hima Dhakal, Young-Ae Choi, Pil-Hoon Park, Hyukjae Choi, Tae-Yong Shin, Hyun Gyu Choi, Taeg Kyu Kwon, Dongwoo Khang* and Sang-Hyun Kim* "Tyrosol attenuates lipopolysaccharide-induced acute lung injury by inhibiting the inflammatory response and maintaining the alveolar capillary barrier" Food and Chemical Toxicology, 2017, 109, 526-533.

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48. Grace Choi, Ming Gao, Dae Sung Lee, and Hyukjae Choi* "Mabikibacter ruber gen. nov., sp. nov., a bacterium isolated from marine sediment, and proposal of Mabikibacteraceae fam. nov. in the class Alphaproteobacteria" International Journal of Systematic and Evolutionary Microbiology, 2017, 67, 3375-3380.

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47. Liang Li, Mahesh Sapkota, Ming Gao, Hyukjae Choi* and Yunjo So* "Macrolactin F inhibits RANKL-mediated osteoclastogenesis by suppressing Akt, MAPK and NFATc1 pathways and promotes osteoblastogenesis through a BMP-2/smad/Akt/Runx2 signaling pathway" European Journal of Pharmacology, 2017, 815, 202-209.

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46. Ji Sun Hwang, Geum Jin Kim, Hyun Gyu Choi, Min Cheol Kim, Dongyup Hahn, Joo-Won Nam, Sang-Jip Nam, Hak Choel Kwon, Jungwook Chin, Sung Jin Cho, Hayoung Hwang* and Hyukjae Choi* "Identification of antiangiogenic potential and cellular mechanisms of napyradiomycin A1 isolated from the marine-derived Streptomyces sp. YP127" Journal of Natural Products, 2017, 80, 2269-2275.

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45. Tu Cam Le, Chae-Yoon Yim, Songhee Park, Nikita Katila, Inho Yang, Myeong Chong Song, Yeo Joon Yoon, Dong-Young Choi, Hyukjae Choi*, Sang-Jip Nam*, and William Fenical* "Lodopyridones B and C from a marine sediment-derived bacterium Saccharomonospora sp." Bioorganic & Medicinal Chemistry Letters, 2017, 27, 3123-3126.

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44. Jaewoo Yoon, So Young Kim, Songhee Park, and Hyukjae Choi* "Characterization of Marinovum faecis sp. nov., an alphaproteobacterium isolated from marine sediment" Antonie van Leeuwenhoek, 2017, 110, 963-969.

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43. Jong Yeong Lee, Jin Kyeong Choi, Na-Hee Jeong, Jeongsoo Yoo, Yeong Su Ha, Byungheon Lee, Hyukjae Choi, Pil-Hoon Park, Tae-Yong Shin, Taeg Kyu Kwon, Sang-Rae Lee, Soyoung Lee, Seung Woong Lee, Mun-Chual Rho, and Sang-Hyun Kim* "Anti-inflammatory effects of ursolic acid-3-acetate on human synovial fibroblasts and a murine model of rheumatoid arthritis" International Immunopharmacology, 2017, 49, 118-125.

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42. Hyun Gyu Choi, In-Gyu Je, Geum Jin Kim, Joo-Won Nam, Sang Hee Shim, Sang-Hyun Kim* and Hyukjae Choi* "Chemical constituents of the root of Angelica tenuissima and their anti-allergic inflammatory activity" Natural Product Communications, 2017, 12, 779-780.

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41. Jin-Hyung Lee, Yong-Guy Kim, Minsu Kim, Eonmi Kim, Hyukjae Choi, Younghoon Kim, and Jintae Lee* "Indole-associated predator-prey interactions between the nematode Caenorhabditis elegans and bacteria" Environmental Microbiology, 2017, 19, 1776-1790.

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40. Weihong Wang, Hiyoung Kim, Rahul S. Patil, Awadut G. Giri, Dong Hwan Won, Dongyup Hahn, Youjung Sung, Jusung Lee, Hyukjae Choi, Sang-Jip Nam, and Heonjoong Kang* "Cadiolides J-M, antibacterial polyphenyl butenolides from the Korean tunicate Pseudodistoma antinboja" Bioorganic & Medicinal Chemistry Letters, 2017, 27, 574-577.

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39. Geum Jin Kim, Jong Yeong Lee, Hyun Gyu Choi, So Young Kim, Eonmi Kim, Sang Hee Shim, Joo-Won Nam, Sang-Hyun Kim,* and Hyukjae Choi* "Cinnamomulactone, a new butyrolactone from the twigs of Cinnamomum cassia and its inhibitory activity of matrix metalloproteinases" Archives of Pharmacal Research, 2017, 40, 304-310.

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2016

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38. Dongyup Hahn, Hiyoung Kim, Inho Yang, Jungwook Chin, Hoosang Hwang, Dong Hwan Won, Byoungchan Lee, Sang-Jip Nam, Merrick Ekins, Hyukjae Choi,* and Heonjoong Kang* "The halicylindramides, farnesoid X receptor antagonizing depsipeptides from a Petrosia sp. marine sponge collected in Korea" Journal of Natural Products, 2016, 79, 499-506.

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37. Hyun Gyu Choi, Hyukjae Choi, Jeong-Hyung Lee, Byung Sun Min, and Jeong Ah Kim* "Anti-Inflammatory activity of a novel acetylene isolated from the roots of Angelica tenuissima Nakai" Helvetica Chimica Acta, 2016, 99, 447-451.

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36. Wonhwa Lee, Sae-Kwang Ku, Songhee Park, Kyung-Min Kim, Hyukjae Choi,* and Jong-Sup Bae* "Inhibitory effect of three diketopiperazines from marine-derived bacteria on HMGB1-induced septic responses in vitro and in vivo" The American Journal of Chinese Medicine, 2016, 44, 1145-1166.

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35. Sajita Shah, Chaemin Lee, Hyukjae Choi, Jaya Gautam, Hyeonjin Jang, Geum Jin Kim, Yu-Jeong Lee, Chhabi Lal Chaudhary, Sang Won Park, Tae-gyu Nam,* Jung-Ae Kim,* and Byeong-Seon Jeong* "5-Hydroxy-7-azaindolin-2-one, a novel hybrid of pyridinol and sunitinib: design, synthesis and cytotoxicity against cancer cells" Organic & Biomolecular Chemistry, 2016, 14, 4829-4841.

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34. Hyukjae Choi, Sae-Kwang Ku, and Jong-Sup Bae* "Inhibitory effect of three diketopiperazines from marine-derived bacteriaon secretory group IIA phospholipase A2" Natural Product Communications, 2016, 11, 1267-1270.

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33. Minsu Kim, Jin-Hyung Lee, Eonmi Kim, Hyukjae Choi, Younghoon Kim, and Jintae Lee* "Isolation of indole utilizing bacteria Arthrobacter sp. and Alcaligenes sp. from livestock waste" Indian Journal of Microbiology, 2016, 56, 158-166.

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32. Byeongjin Jung, Sae-Kwang Ku, Ming Gao, Kyung-Min Kim, Min-Su Han, Hyukjae Choi,* and Jong-Sup Bae* "Suppressive effects of three diketopiperazines from marine-derived bacteria on TGFBIp-mediated septic responses in human endothelial cells and mice" Archieves of Pharmacal Research, 2016, 39, 843-854.

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31. Seongdo Jeong, Sae-Kwang Ku, Gahee Min, Hyukjae Choi, Dong Ho Park, and Jong-Sup Bae* "Suppressive effects of three diketopiperazines from marine-derived bacteria on polyphosphate-mediated septic responses" Chemico-Biological Interactions, 2016, 257, 61-70.

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2015

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30. Mahesh Sapkota, Liang Li, Hyukjae Choi, William H. Gerwick,* and Yunjo Soh* "Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways" European Journal of Pharmacology, 2015, 769, 100-109.

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29. Kyo Bin Kang, Gao Ming, Geum Jin Kim, Thi-Kim-Quy Ha, Hyukjae Choi, Won Keun Oh, and Sang Hyun Sung* "Jubanines F-J, cyclopeptide alkaloids from the roots of Ziziphus jujuba" Phytochemistry, 2015, 119, 90-95.

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28. Inho Yang,† Hyukjae Choi,† Sang-Jip Nam,* and Heonjoong Kang* "Two indole-alkaloids from a Korean marine sponge Spongia sp." Bulletin of the Korean Chemical Society, 2015, 36 (8), 2120-2123. (†Co-first author)

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27. Inho Yang,† Hyukjae Choi,† Sang-Jip Nam,* and Heonjoong Kang* "A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp." Archives of Pharmacal Research, 2015, 38 (11), 1970-1974. (†Co-first author)

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26. Hyukjae Choi*, and Dong-Chan Oh* "Considerations of the chemical biology of microbial natural products provide an effective drug discovery strategy" Archives of Pharmacal Research, 2015, 38 (9), 1591-1605.

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25. Jung-Rae Rho, Gurusamy Subramaniam, Hyukjae Choi, Eun-Hee Kim, Sok Peng Ng, K. Yoganathan, Siewbee Ng, Antony D. Buss, Mark S. Butler, and William H. Gerwick* "Gargantulide A, a complex 52-​membered macrolactone showing antibacterial activity from Streptomyces sp." Organic Letters, 2015, 17 (6), 1377-1380.

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24. Hiyoung Kim, Inho Yang, Shin-Young Ryu, Dong Hwan Won, Awadut G. Giri, Weihong Wang, Hyukjae Choi, Jungwook Chin, Dongyup Hahn, Eunhee Kim, Chulkyeong Han, Jihye Lee, Sang-Jip Nam, Won-Kyung Ho, and Heonjoong Kang*, "Acredinones A and B, voltage-dependent potassium channel inhibitors from the sponge-​derived fungus Acremonium sp. F9A015" Journal of Natural Products, 2015, 78 (3), 363-367.

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23. Jaewoo Yoon, Yujin Jo, Geum Jin Kim, and Hyukjae Choi*, "Gramella lutea sp. nov., a novel species of the family Flavobacteriaceae isolated from marine sediment" Current Microbiology, 2015, 71 (2), 252-258.

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22. Weihong Wang, Tae Gu Lee, Rahul S. Patil, Bora Mun, Inho Yang, Hiyoung Kim, Dongyup Hahn, Dong Hwan Won, Jihye Lee, Yehee Lee, Hyukjae Choi, Sang-Jip Nam, and Heonjoong Kang*, "Monanchosterols A and B, bioactive bicyclo[4.3.1]steroids from a Korean sponge Monanchora sp." Journal of Natural Products, 2015, 78 (3), 368-373.

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21. Dong-Young Choi, and Hyukjae Choi*, "Natural products from marine organisms with neuroprotective activity in the experimental models of Alzheimer's disease, Parkinson's disease and ischemic brain stroke: their molecular targets and action mechanisms" Archives of Pharmacal Research, 2015, 38 (2), 139-170.

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20. Bora Mun, Weihong Wang, Hiyoung Kim, Dongyup Hahn, Inho Yang, Dong Hwan Won, Eun-hee Kim,, Jihye Lee, Chulkyeong Han, Hyunji Kim, Merrick Ekins, Sang-Jip Nam, Hyukjae Choi*, and Heonjoong Kang*, "Cytotoxic 5α,​8α-​epidioxy sterols from the marine sponge Monanchora sp." Archives of Pharmacal Research, 2015, 38 (1), 18-25.

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2014

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19. Hiyoung Kim, Inho Yang, Rahul S. Patil, Sinwoo Kang, Jihye Lee, Hyukjae Choi, Min-Sun Kim, Sang-Jip Nam, and Heonjoong Kang*, "Anithiactins A-C, modified 2-phenylthiazoles from a mudflat-derived Streptomyces sp." Journal of Natural Products, 2014, 77 (12), 2722-2725.

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18. Inho Yang,† Hyukjae Choi,† Dong Hwan Won, Sang-Jip Nam,* and Heonjoong Kang* "An antibacterial 9,11-secosterol from a marine sponge Ircinia sp." Bulletin of the Korean Chemical Society, 2014, 35 (11), 3360-3362. (†Co-first author)

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17. Bailey Miller, Aaron J. Friedman, Hyukjae Choi, James Hogan, Andrew J. McCammon, Hook Vivian, and William H. Gerwick*, "The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L" Journal of Natural Products 2014, 77 (1), 92-99.

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2013

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16. Lena Gerwick, Paul Boudreau, Hyukjae Choi, Samantha J. Mascuch, Francisco A. Villa, Marcy J. Balunas, Karla L. Malloy, Margaret E. Teasdale, David C. Rowley and William H. Gerwick*, "Interkingdom signaling by structurally related cyanobacterial and algal secondary metabolites" Phytochemistry Reviews 2013, 12 (3), 459-465.

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15. Hiyoung Kim, Jungwook Chin, Hyukjae Choi, Kyungryul, Baek, Tae-Gu, Lee, Seong Eon Park, Weihong Wang, Dongyup Hahn, Inho Yang, Jihye Lee, Bora Mun, Merrick Ekins, Sang-Jip Nam*, and Heonjoong Kang*, "Phosphoiodyns A and B, unique phosphorus-containing iodinated polyacetylenes from a Korean sponge Placospongia sp." Organic Letters 2013, 15 (1), 100-103.

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2012

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14. Eun Ji Kim, Jong Hyun Lee, Hyukjae Choi, Alban R. Pereira, Yeon Hee Ban, Young Ji Yoo, Eunji Kim, Je Won Park, David H. Sherman, William H. Gerwick*, and Yeo Joon Yoon*, "Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product" Organic Letters 2012, 14 (23), 5824-5827.

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13. Hyukjae Choi, Emily Mevers, Tara Byrum, Frederick A. Valeriote, and William H. Gerwick*, "Lyngbyabellins K–N from two Palmyra Atoll collections of the marine cyanobacterium Moorea bouillonii" European Journal of Organic Chemistry 2012, 2012 (27), 5141-5150.

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12. Weihong Wang, Yehee Lee, Tae Gu Lee, Bora Mun, Awadut G. Giri, Jihye Lee, Hiyoung Kim, Dongyup Hahn, Inho Yang, Jungwook Chin, Hyukjae Choi, Sang-Jip Nam*, and Heonjoong Kang*, "Phorone A and isophorbasone A, sesterterpenoids isolated from the marine sponge Phorbas sp." Organic Letters 2012, 14 (17), 4486-4489.

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11. Hyukjae Choi, Samantha J. Mascuch, Francisco A. Villa, Tara Byrum, Margaret E. Teasdale, Jennifer E. Smith, Linda B. Preskitt, David C. Rowley, Lena Gerwick, and William H. Gerwick*, "Honaucins A−C, potent inhibitors of inflammation and bacterial quorum sensing: synthetic derivatives and structure-activity relationships" Chemistry and Biology 2012, 19 (5), 589–598.

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10. Jungyeob Ham, Hoosang Hwang, Euno Kim, Jeong-ah Kim, Sung Jin Cho, Jaeyoung Ko, Woojin Lee, Jaehwan Lee, Harish Holla, Joydeep Banerjee, Sukho Kim, Inho Yang, Hyun Joo Lee, Kyoungjin Shin, Hyukjae Choi, Sang-Jip Nam, Jungae Tak, Dongyup Hahn, Taekyung Oh, Dong Hwan Won, Tae Gu Lee, Jihye Choi, Mi Sun Park, Chaok Seok, Jungwook Chin and Heonjoong Kang*, "Discovery, design and synthesis of Y-shaped peroxisome proliferator-activated receptor δ agonists as potent anti-obesity agents in vivo" European Journal of Medicinal Chemistry 2012, 53, 190–202.

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9. Kyoungjin Shin, Jungwook Chin, Dongyup Hahn, Jaehwan Lee, Hoosang Hwang, Dong Hwan Won, Jungyeob Ham Hyukjae Choi, Ensoo Kang, Hiyoung Kim, Moon Kyeong Ju, Sang-Jip Nam* and Heonjoong Kang*, "Sterols from a soft coral, Dendronephthya gigantean as farnesoid X-activated receptor antagonists" Steroids 2012, 77 (5), 355–359.

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8. Hyukjae Choi, Philip Proteau, Tara Byrum, Alban R. Pereira, and William H. Gerwick*, "Cymatherelactone and cymatherols A−C, polycyclic oxylipins from the marine brown alga Cymathere triplicata" Phytochemistry 2012, 73 (1), 134–141.

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7. Karla L. Malloy†, Hyukjae Choi†, Catherine Fiorilla, Fred A. Valeriote, Teatulohi Matainaho and William H. Gerwick*, "Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction" Bioorganic Medicinal Chemistry Letters 2012, 22 (1), 683–688. (†Co-first author)

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2011

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6. Niclas Engene, Hyukjae Choi, Eduardo Esquenazi, Tara Byrum, Francisco A. Villa, Zhengyu Cao, Thomas F. Murray, Pieter C. Dorrestein, Lena Gerwick and William H. Gerwick*, "Phylogeny-guided isolation of ethyltomonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera" Journal of Natural Products 2011, 74 (8), 1737–1743.

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5. Niclas Engene, Erin C. Rottacker, Jan Kaštovský, Tara Byrum, Hyukjae Choi, Mark H. Ellisman, Jiří Komárek and William H. Gerwick*, "Moorea producta gen. nov., sp. nov. and Moorea bouillonii comb. nov., tropical marine cyanobacteria rich in bioactive secondary metabolites" International Journal of Systematic and Evolutionary Microbiology 2012, 62, 1171–1178.

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4. Niclas Engene, Hyukjae Choi, Eduardo Esquenazi, Erin C. Rottacker, Mark H. Ellisman, Pieter C. Dorrestein, and Willam H. Gerwick* "Underestimated biodiversity as a major explanation for the perceived rich secondary metabolite capacity of the cyanobacterial genus Lyngbya" Environmental Microbiology 2011, 13 (6), 1601–1610.

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3. Hyukjae Choi, Hoosang Hwang, Jungwook Chin, Euno Kim, Jaehwan Lee, Sang-Jip Nam, Byoung Chan Lee, Boon Jo Rho and Heonjoong Kang* "Tuberatolides, potent FXR antagonists from the Korean marine tunicate Botryllus tuberatus" Journal of Natural Products, 2011, 74(1), 90–94.

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2010

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2. Hyukjae Choi, Alban R. Pereira, Zhengyu Cao, Cynthia F. Shuman, Niclas Engene, Tara Byrum, Teatulohi, Matainaho, Thomas F. Murray, Alfonso Mangoni* and William H. Gerwick*, "The hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria" Journal of Natural Products 2010, 73 (8), 1411–1421. (2010 the Arthur E. Schwarting Award)

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1. Hyukjae Choi, Niclas Engene, Jennifer E. Smith, Linda B. Preskitt and William H. Gerwick*, "Crossbyanols A–D, toxic brominated polyphenyl ethers from the Hawai‘ian bloom-forming cyanobacterium Leptolyngbya crossbyana" Journal of Natural Products, 2010, 73 (4), 517–522.